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More calories out than calories in to lose weight all over. If she wants the muscle in her legs to decrease, she needs to let them atrophy, which means no lifting.
High reps/low weight to "tone" is a myth.
She could also try bulking up her lower torso/waist a little tp change hip/waist ratio by working abs, lower back and obliques, but I doubt that would accomplish much.
If you want a good calorie burning aerobic exercise that avoids the leg muscles, try swimming. Most of the motive power for swimming comes from the upper body.
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