When you ran the virus-checker, was the computer in safe mode? Many viruses, etc can load up during boot so it's too late once the computer starts. I had this problem once, so I
a) updated all the definitions of the virus-checker, anti-spyware, etc.
b) rebooted the computer in safe mode (hold down the ctrl button when the computer is starting up, then choose safe mode)
c) run all the checkers in safe mode.
d) reboot back into normal mode
This should help get rid of the more stubborn kind of problems
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