First of all, I hate a lot of labels (including this one) because to the extent that they are currently used, they are completely useless as they frequently require a definition anyway and therefore are not conducive to understanding (among other problems). Sorry, just had to get that out of the way.
I would not alter my body in most ways. Maybe genetic modification to improve my eyesight (20/10 would be awesome!
), as well as one or two other things which I consider to be genetic defects. As for the rest, it's iffy at best. Really depends what would be available, how invasive it would be, and whether it would change me in what I consider to be a "fundamental" way (in which case I would opt against it).