My wife and I share the bathroom all the time. I usually try to avoid being there when she goes #2, but sometimes circumstances do not permit that. She doesn't mind it when I go #2, though, except for the smell
Incidentally, sharing the bathroom with my wife is how I've gotten over my anxiety of using those public urinals. It used to be the case that I would just seize up if I tried to use one, but now I can let it go with ease, even if there's someone standing next to me.