I think it all depends on how much you care about the subject, and how patient you are in attaining your goals. If you want to be a *professional* particle physicist, or baseball player, or tamborine player, or whatever - then time is crucial. Not too many people are going to hit the Pro Leagues or start a tenure track position at the age of 50. However, in my opinion, if you just want the knowlede / skill, you can start anytime and get as far as you can, within limits of physical/mental degradation, before you pass on into the wild blue yonder. I know too many people who started off in something like Classic Greek Studies, and switched into things like parallel computing and meta-data management at ages of 40+ - or who went from being science team captains to whip-ass guitarists later in life to believe it isn't possible.
Do you want it? How badly? Will you wait in devotion to the knowledge, not the appearance of knowledge?
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