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Lots of good advise so far.
For me running is the best way to burn those calories. And doing a little strength training and building up muscle in other areas will only help.
Losing weight is simple. Some people make it out to be so difficult. You just have to remember it's calories in vs. calories out.
To answer your questions... Stompy was spot on about gradually easing into runnning. You have to give you body time to adjust to the stresses of running. Especially if you have not maintained an exercise program, and are overweight.
If you are overweight, and are worried about the effects. You can always start out cycling to drop a few pounds first.
c172g was also right about running shoes. It is very important to get a good pair. You can either order them online, such as his suggestion of RRS. Or you can search out a local running store. If they are a good one, they will put you on a treadmill and analyze your gait. And then make suggestions for shoes from there.
You can get good affects from any cardio done right. (time/stress) But if you want to get good at running, you will not get that from cycling.
As for runners high, yeah it happens. It seems to only hit me when on a run longer than 6 miles. It feels as if you are superman, each hill you come to you just want to go faster up it. It's a great feeling... But not something that happens very often.
Just remember to not start out to fast. There are some good basic articles on runnersworld.com
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Disco Duck...
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