There is no perfect configuration that satisfies every system and purpose. If I'm just running one game and its performance is paramount (say Lanparty for the night) I'd disable VM entirely. However, if it's a multi-purpose system then VM is needed for apps that require it.
DisablePagingExecutive just tells the system not to page out its structures when hungry or numerous apps make requests we might consider less important. Ideally you could set an "Apps,BeNiceDamnit" flag, but all we have is a "System,Don'tLetAppsBullyYou" flag. Not perfect, but it's generally better when switching around between tasks.
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