I'm pretty far into the game now and I'm still impressed. The Difficulty of the game is set perfectly. Crosshairs would make it a little easier but that really doesnt matter when the shotgun is your weapon of choice. Save your pistol for the last mob standing
YaWhateva to get passed that...Spoiler:
shoot him until he bends over and the virus comes out of his back, run behind him and it'll let you climb up his back and rapidly tap the button to slice him up. You only need to do it twice.