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I am on Lexapro, and I noticed a difference in about 3-4 days. I started on it after my brother passed away this summer, although I have always suffered from depression. I don't know if this will help you, but I feel like a completely different person since I've started taking it. I worry less, I sleep better, I have an interest in things, I have a general better outlook on life. One bad thing about antidepressants is they tend to lower the sex drive and sometimes lessen the ability to have an orgasm; this doesn't always happen but its a common side effect.
I know it's difficult to deal with someone with depression, but hang in there. Hopefully the Lexapro will help and your girlfriend will start to feel better. Depression sucks for the person dealing with it AND the people who love that person. You can always come here and vent/get something off your chest. I'll certainly listen!!
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