I wonder whether anyone is 100% comfortable at the beginning. They seem so fragile when you first pick them up - but watch the midwives in hospital throw them around and you quickly realise they aren't as breakable as they seem.
I think having support from another/others will increase your comfort level. Both my wife and I have times where we just don't want to change/feed/settle - but it rarely happens that we are both feeling this way.
Think about it - you get more training to learn to drive a car - children are heaps more complex