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Someone mentioned .45 ACP not being good for hunting; that's not entirely accurate as far as I know. The main reason that .45 ACP is generally a shorter-range round is because of the firearms in which it is used. A good example of the possible longer-range possiblities of the calibre is the DeLisle carbine, which is a silent bolt-action carbine with a maximum effective range of between 200 and 400 metres (I don't remember the exact range). If you could find a pistol with a long enough barrel, I'm sure you could hunt with it.
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