Humans will have to leave the Earth eventually if they wish to survive. It's best to start work on that as soon as possible. However, a trip to Mars is somewhat pointless.
Instead of spending $12B on a trip that will amount to a few days on Mars we should be spending it on making self-sustaining life possible in space. We need to facilitate gravity to avoid detrimental effects of space life first. Next we need a way to cultivate food in space. After that we need to work on fast propulsion, getting us as close to light speed as possible. As we approach that barrier, we can work on going past that barrier because that is what will make interstellar travel possible.
None of that is accomplished by going to Mars for a field trip.
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