I had to make this exact choice a while ago - but if you know what you're doing I'd go with PHP. Access and Microsoft-type solutions might have the nice point-and-clickiness, but PHP is nowadays an extremely powerful language and works very well with mySQL for database apps. Best of all it's a free solution and works exceptionally well cross-platform (my app has been served from Windows, Linux and Mac OS without anyone knowing the difference)
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I can't understand why people are frightened of new ideas. I'm frightened of the old ones. -- John Cage (1912 - 1992)
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