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I guess my # 1 reason is that I've never liked the altered consciousness that I have when I get a buzz from Alcohol, or medication such as morphine or codine when I was hospitalized. I don't expect I would really like the feeling that I could get from pot.
I have felt just a little curious about what it would be like but that curiousity has been overidden by a number of things.
2. Lack of knowledge where to acquire the drug.
3. Lack of desire to spend any money on something so "experimental" to me.
4. Fear or Addiction.
5. Sense of responsibility in other areas of my life and fear of failing in any area because of the altered mental ability.
6. Knowledge of the physical affects that the drug causes in the human body, esp. the brain.
I believe that's reason enough to avoid it all together. For most of these same reasons, except #2 I have avoided cigerettes and I rarely drink. Best to avoid the problems that can arise in the first place.
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"Always learn the rules so that you can break them properly." Dalai Lama
My Karma just ran over your Dogma. 
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