If you want to clean/re-condition your ball-type mouse, here is what you need to do.
Pop the mouse ball out of the mouse. Locate and remove all the screws from the mouse. Once you have the mouse apart, you will see a small circuit board that has two rollers which are attached to two large wheels. You need to clean those rollers with a QTip soaked in Isopropyl Alcohol. Then, use compressed air to clean out the tiny holes around the circumference of each of those two plastic wheels attached to the rollers. Then, shoot a bit of compressed air into the optical sensors that each of the wheels pass through. Finally, clean the ball itself with alcohol, and reassemble.
Good as new (assuming you don't end up with 'spare' parts!)