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I haven't had any issues with it, and like ShaniFaye, the others all gave me headaches. Note that the Coca-cola product C2 has about 3 different artifical sweeteners in addition to the sugar, not just Splenda; the Pepsi version Edge only has Splenda and real sugar.
I initially thought that Splenda was giving me digestive issues, but it turned out it was the wheatgrass.
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