Really enjoyed the first episode. It's too early to make to many guesses, but I'll throw some of mine in anyway.
I think Charlie+ Drug problem is a red herring. Way too obvious. However, I think he left something in that front bathroom and that's why he was so anxious to go with Jack and Kate.
Rumor has it that not everyone who is on the beach was on the plane...
Did anyone notice while jack was giving his "count to five" speech that there was a tatoo on his shoulder with the number 5 in it? Just wondering.
I just hope they don't kill off the fat guy too soon. Lord, the fat guy is always one of the first to go.