Depends on what you want to do with it. Every one of them does things differently, and some do certain things better than others.
For just a weblog type deal, I prefer Wordpress. If you are looking for a full-blown CMS, zope/plone is probably what you want. There are hundreds of choices in between. You can even write your own basic one if you want, there isnt that much to a simple one.
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"Good people do not need laws to tell them to act responsibly, while bad people will find a way around the laws."
--Plato
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