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One theory I heard about the start of AIDS had to do with smallpox. In Africa, they used either apes or chimps(can't remember which), to grow a smallpox vaccine. They think that it was possibly passed on to people through vaccinations. Supposedly there is a SIV(simian immunodeficincy virus) that was thought to be incapable to pass from ape to man, which may have mutated to allow transmission.
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