Jeeps don't have a very good reliability record compared to other American cars, let alone comparing them to Japanese. The Highlander is a great vehicle, but doesn't have a lower differential. So if any of the mountain trips require some 4-wheeling, then the Highlander is not the SUV for you. The 4Runner would be however, as would the pathfinder. Both are good vehicles and would suit all your purposes great. The 4Runner however, is a better off-road vehicle and has more ground clearance. If you don't need to lower diff, then I would go with the Highlander, it's a bit more roomy than the 4Runner and Pathfinder (With the exception of the 2003 or newer 4Runner).
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