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The connection between Accutane treatment and depression is minimal. If there is a link, it is probably going to be hard to be very sure of because many patients taking Accutane are teenagers. Moodswings and teenagers come hand and hand.
I read a little on this, but I don't remember much, so I'll stick to my anecdotal evidence (READ: just a story)
I took Accutane. Worked amazingly well, and my only side-effect was dry lips. If you keep chapstik on hand EVERYWHERE you'll do okay. I've always been an emotional rock though, so not the best.
2 of my friends and my sister were on accutane. Although I never asked them about depression during or after treatment, I don't remember any unusual attitudes in any of them.
This is only my experience. It doesn't count for much, if anything, but it was safe and extremely effective for me and my friends.
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