Everything you buy outside of Dell has to conform to the ATX form factor.
That Dell motherboard, however, may not have the proper mounting holes or ATX power connector. Dell will use proprietary mounting holes/clips and plugs to force you into buying upgrades from them.
BUT, this is not true for all Dell motherboards. In higher end Dell systems, they'll still use ATX compliant parts. A good example of this is their Poweredge 400 servers. The case you get isn't ATX since the motherboard isn't held in with screws through the mobo, but everything else in the case is ATX compliant (including the motherboard).
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