antidepressants
 

Anyone want to share their experiences on antidepressants. I'm on celexa right now. I feel pretty good, but I'm also realizing that happiness, at least the feeling, is not all that it is cracked up to be. It's a gloss over what is really important. However, I feel terrible when I'm not on the medication. I'm only on the starting dose, and I'm thinking that instead of upping the dose I will add a low dose of Wellbutrin into the mix. I have no concrete rationale for that, but whatever. I have more to say. I'll say it later.

ummmmmmm

as a person on massive meds for 24 years (avg 8 to 11 pills once, five at night) i say don't fuck with chemicals of any kind without consultation of your own research, advice from doctors and the like.

for me, in 2000 i was fucking coming unglued. i literally got so anxious one day in a dr. office due to supressed memories i was shaking almost as if siezuring and my voice dropped to a whisper. i felt beyond high and almost passed out.... so on. the doc told me i needed help. soon.


i did. and started Zoloft. 3-4 weeks later i dealt better. now in 2003 i am doing much, much better. and i control almost all of my fear.

thing is......

1) every med affects every person differently. some help, some do nothing, some make it much worse

2) placebos. if you convince yourself that a tylenol is a miracle cure, it will pretty much be one

3) we're changing chemicals. we do not know what chemicals they are and how it makes us feel in hindsight. depression is a vast mystery medical wise.

4) yer going to feel weird for a long time. Zoloft stays in your system for 3-4 weeks at least.


the worse answer you can get is the one you need. you gotta wait it out.

there is hope though. stay strong and contact me if you need to vent.


nobody at all should deal with this shit alone.

It is my opinion that SSRI and SSRI-like medication used for first-line treatment of depression and anxiety is unnecessary, expensive, and dangerous.

That said, my personal experience has been with Prozac, Paxil, and an easily obtainable proprietary antidepressant regimen.

Prozac and Paxil, at best, did nothing to help.

The antidepressants I'm on now work great without any of the risks and side-effects that come with usual antidepressants. My antidepressants protect me from deeply depressive/manic episodes. I will soon be using Klonopin daily for anxiety.

I used to preach about this regimen to people who were stuck on SSRIs and similar medication. I was bothered that people were taking drugs they knew nothing about, that didn't help them, and sometimes even made thing worse, and they continued to take them. I keep my mouth shut about it now, not many people seem to be willing to trust anyone that doesn't have an M.D., competency be damned.

I've been on Zoloft for about a year now. It's given me the drive to get out and do something with my life... Which was apparently become an alcoholic. :)

i used zoloft for about 8 months or so, and it kept me from getting the panic attacks i had been getting, but did nothing with depression. one day i decided to stop taking it, and a little while after that i felt great. stayed undepressed for a while. then i got depressed again, got into a car accident (completely unrelated) and felt great. i just read an article that suggests that taking folic acid could work in prevention of depression for some people, and the hospital had me on it to raise my hemoglobin count, so i'm wondering if that had anything to do with it. we'll see...

Butthead, could you please go into more detail about the things you discussed in your post. Why do you think ssri's are dangerous? I know celexa works for me. I could feel it kick in one day, and when I stopped taking it once for a month I could feel the horrible feelings return. I know it wasnt placebo.

I'll get back to you shortly, hopefully. I think there may be significant risk when using SSRIs period, but more especially for first-line treatment and especially if a "chemical imbalance" hasn't been determined.

SSRIs generally take 4-6 weeks for antidepressant/anxiolytic effects (with the exception of maybe Lexapro, active isomer of Celexa), although side-effects may appear on the first day. Consider that it takes time for clinical effects that you felt on the first day and your apparent belief that it was working because you felt terrible after abruptly stopping after a month (SSRIs can cause withdrawal).

But, maybe I'm wrong for some reason. A few months ago I would have been able to tell you a whole lot more right now, but due to chronic pot smoking and lack of studying (and other factors), it's going to take some time for me to check references.

I was on Zoloft for awhile, it made me feel depress really bad. Got off it. For about a year nothing. Now I'm on Wellbutrin, never felt better. I still have bad days, but not as bad as before. Thing is my creatine went up to 1.9 after starting on it. I have a kidney transplant so having a high creatine is scary. It dropped to 1.8, but still. The doctor says the med wouldn't affect my kidney. If it doesn't go down I will asked the new doctor it it could be affecting. On the plus side I lost 10 pounds.

Reactions to meds are so intensely individualized that any anecdotes you get are going to be completely meaningless for your own experience.

That said, since you asked, I'm on Paxil and have been since December to treat panic attacks and mild depression. I'm also doing cognitive behavior therapy, which is where the real "juice" is as far as I'm concerned. The Paxil is merely there to keep my brain chemistry stable while I relearn how to think about my life and how to react to things. As soon as I can I'm going to be tapering off the Paxil. However, I've had a really great experience with it - I don't feel like it's causing "false" emotions. I feel more like I'm able to be happy when I'm happy, and not anxious about what I should be worrying about instead of being happy. I am able to feel sad, bored, angry, nervous, tense, but the emotions are appropriate to the situation I'm in. The side-effects were minimal, and this past Christmas was the first one I didn't cry at. When my brother died a few months ago I was able to be there for my family before and after my brother's death, and mourn him, and be myself instead of being a slave to my anxieties.

Ah a subject near and dear to my heart. I never had need of them until I started this damn job. I have tried some of the more common ones mentioned. Now I am on Buspar. Seemed to do a pretty good job, but lately them seem to be slipping a little. I don't know maybe it is time for a change. Either job or pills.

there is also one huge misconception concerning these drugs: They do not make us happy.

There is no happy pill (or at least a legal one). like lurkette said with Paxel, it hates more with chemical stability and she seems to be saying something similiar to myself.

after i gave in and started medicating and talking to friends i started 'waking up' and seeing how i had quit doing Fun Activities. i thought to myself 'reading is boring, the net is boring, games are starting to bore me... life is boring me.' i realized that that was a dangerous thought and and alien one. so i forced myself to re-introduce myself to my old hobbies.

i enjoyed them!

it was as if i were punishing myself without realizing it and simply ruining all hope for fun.

if Zoloft had to make me not be depressed then yeah i'd say it failed. it can help, not cure.

after taking Zoloft i simply started thinking more clearly and my thoughts were less dire. the rest is up to me. and it should be. our lives would suck if we could take a pill and be happy. we'de turn into sheep in a heartbeat.


wtf is an SSRI?

I have been on Zoloft for about three years now and for some reason thought I could just stop taking it....
Obviously I cannot function properly without it, so I am picking up my refill Tomorrow morning.
I have had good luck on it, meaning it has controlled my depression and panic attacks, but I do not like the side effects....So I guess I will have to try and deal with them again.

Actually, the old antidepressants such as d-amphetamine elevated moods very quickly, similar to my antidepressants.

But in effect, what you are saying is very true. Most people, when seeing a psychiatrist, are likely to be put on an SSRI/TCA or similar medication which will not elevate mood similarly to amphetamine. Clinical effects are supposed to be subtle with SSRIS and TCAs.

An SSRI is a drug belonging to a group of drugs known as selective-serotonin reuptake inhibitors. Examples of SSRIs include Prozac (fluoxetine), Paxil (paroxetine), Zoloft (sertraline), Luvox (fluvoxamine), etc. These block serotonin reuptake sites, preventing serotonin from being taken back up into the presynaptic neuron from which it was released. This increases synpatic serotonin and ideally will result in more serotonin attaching to postsynaptic receptors.

SSRIs may work for some, but they are not the only things that do.

I am very aware of how I'm feeling. I felt it kick in at about three weeks after I started taking it, before that I was up and down. When I stopped, I tapered off, and even after I stopped taking it completely I felt pretty good, but after about three weeks of being off it I started feeling bad. I have analyzed the information and I'm sure it's not placebo. However I think there is too much serotonin in the synapse now, and that whatever feelings that causes are over shadowing other ones. I still can't feel deep emotion, like when I look at the clouds. When I was depressed I felt love. Now I don't feel it as much, but I'm happier, not over all, just the feeling of happiness is stronger. I'd rather feel the love than the happiness. That's why I'm going to see if I can get on WB instead of upping the celexa, get that norepinephrine flowing. I don't really know if it works that way.

How did any of you know when you needed to see a psychiatrist or get on an antidepressant? I personally think I'm kinda screwed up on more than one corner.....seems like most of the time I feel ultra-overwhelmed with the world and feel like I'm drowning in simply everyday life. I'm not suicidal or anything, it's just that the overload of stress and depression is trashing my physical health (stress-related heart problems and I just turned 25) and I don't really know how or who to talk to about it. I know I stress out about things most people wouldn't, but nothing in my job or home-life would ever get done if I didn't keep on it and do it personally. I guess I'm just wondering if the antidepressants are something that would help me keep from feeling like the ocean of life isn't closing over my head faster than I can tread water. I don't think I made any sense in this post, but I appreciate being able to offload a little of this off my mind.

On Celexa also. Have been on for a few years and honestly can't remember why I didn't like the others (Prozac, Paxil, and Zoloft were tried and discarded). In any case, Celexa seems to work the best for me though I go through occasional periods of noncompliance i.e. suddenly wake up convinced that I don't need it (a very common phase of taking any sort of mood stabilizing meds, in my limited experience). Haven't run across anyone on Celexa (rarely met anyone who even heard of it) so, startled as I am, thought I'd make this my first ever post to TFP -- be glad to trade notes anytime.

I've just started celexa 20mg dose. The side effects so far haven't been too bad although I’ve got some nasty insomnia and it's messed up my sleeping patterns big time.

I was on paxil for a year and became thoroughly "addicted". Tapering off from that shit was the worst time of my life.

i think they are way fucking over-prescribed.

your thought is based on what? someone elses? statistics?

i've stayed away from as many chemicals as possible, and find that music is a great as an anti-depresant. And i am glad that i have this medium which i can get so much out of.
its important to not become reliant on chemicals and take them moderatly. I've also heard from people that some yoga or other stress relief technique is very good for clearing the mind and becoming at peace with yourself, and generally happy. Also excercising is good way to release some natural chemicals in your system (i think they're endorphins, tho i dunno) and they do make you feel "good"
Never fill the void in your life with a product!
my adviece is to try to use more natural outlets on relieving the metaphorical pain that is life

Your post juxtaposed with your signature made me laugh :). But i do agree with what you've said. I've tried, and still do everything to try and fix my depression naturally but it just didn't cut and i felt that if i didn't start with the meds again, i wouldn't be around much longer.

This is the kind of judgment I would pass on people on meds before I discovered that I "needed" them myself. For some people, these methods you describe work. However, for many others there is an actual chemical imbalance in the brain that is too severe to be dealt with with yoga and music. Much of depression and anxiety are cognitive and so can be dealt with through therapy or spiritual methods; however, for some people the therapy or yoga or whatever are simply not effective if you've passed some critical point, and you need the drugs to "reset" your brain chemistry to the point where you can function and get back on track. Exercise plus therapy has been shown to be as effective as SSRIs alone for people with MILD depression; however, for people with severe depression, chemicals are often the only option. I know you didn't intend it this way, but your statement simply makes people who have chosen medications to treat depression feel worse - there's already this horrible feeling of being out of control of your own thoughts and emotions, and to have someone say "if only you tried harder to control things through yoga and music you wouldn't need the drugs"....well, you might as well tack on "you losers" to the end of the sentence. Do you think we don't TRY those things first? Do you think we say "oh goodie, I'm clinical now, I can have drugs!!!" Drugs are often the course of last resort for people who have tried everything else. This is not simply a case of the "blah's" that we are treating, turning to drugs because we can't deal with life. This is an overwhelming feeling of hopelessness and worthlessness and panic that persists despite the fact that we know better! So don't be so quick to judge us.

no, no sorry. That was not my intention. Its just i was reading through and no one was really talking about any kind of natural or common everyday things to help you become at peace with yourself (other than thearpy). And i kinda naively assumed that no one had thought of anything else and just jumped to a last case scenario. sorry.
I appreciate that for some people, they need treatment because there is actually an imabalance in the brain which needs to be artifically corrected, or that its so serve that its a last case scenario. Fortunalty thats not the case for me, and i am empathetic with you and everyone else.

Also i am not judging anyone, and thats not my agenda. I was just saying what helps me and what works for me. Using judgement and judging has a connatations of some level of superiority on my part, and i remind you and everyone that i am not better than you and your not better than me.

lol, i am not sure if you're familar with bill hick's musings and concepts, but that little cut refers to a "positive" drug story. And yeah, no one seem to be disscussing other methods of anti-depressants, so yeah i was just saying what i use. I don't and never want to come across with a holier than thou attitude.

i'll finish off with another quote from the great man bill hicks.

"Here is my final point. About drugs, about alcohol, about pornography and smoking and everything else. What business is it of yours what I do, read, buy, see, say, think, who I fuck, what I take into my body - as long as I do not harm another human being on this planet?"

Mr Hicks was full of much wisdom.

I am fortunate not to have to need the help of medicine to be "Normal" I know first hand the difficulties with the medicines, levels, types and dosages needed to be "Normal" I have seen the effects of over perscribed, underprescribed and wrong meds, non working meds from those close to me. And I know first hand it no joke or laughing matter, but a difficult process to find the right mix or medicine that works for the individual, because they work so differently on each of them. I can just theorize the reason the medicine is so over prescribed is that they don't have enough information to be able to say, hey just take this one and wall-la..
All I know when they work, it gives my friends and loved ones the ability to function, and when they don't they have a difficult time. I am just blessed that I don't have to go though this process.

you can get off of it, dudette, it just can't be done cold turkey.

best of luck!

butthead.... um. i asked wtf did it mean. now.. wtf did YOU mean? english, dude!

music is a major, major way to mix emotions up. i have been meaning to post a thread related to this over a month.


all of these posters who 'have the right answer' worry me... i know you throw in your opinion, but this is a very, very delicate subject.


medication can work. medication can kill. it all varies: this is why you start low and pay attention.


what amuses me in a sad way is so many people avoid the 'happy pills' and then oftentimes drink excessive amounts of alcohol. yeah. that's safe and smart...

For a basic explanation, the Zoloft commerical does a fair job.

For people taking SSRIs are considering taking SSRIs: be sure to have your doctor find out as much as possible what your serotonin levels are and to remember that there is no set standard for serotonin levels. Remember that SSRI drugs like Prozac are there to correct a supposed chemical problem and that taking an SSRI before making sure of those two things is little more than quackery.

And that 5HTP, an over the counter protein, is comparable in efficacy to SSRIs and in many countries is held in favor over SSRIs because of this and its lack of SSRI-like side-effects.

now, I feel better. Thanks Baby!:icare:

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I take paxell, it works, no bad side affects, it's all good

seems like everybody that goes to the doctor, or gets arrested, or has trouble in school, or gets married, or has children gets antidepressants. it's like antibiotics for every cold. doctors don't wanna fuck with people, don't really know what's wrong with them, and can't make them happy so they give 'em a prescription.

agreed.
i was on paxil for five months and prozac for seven... i went off them and hated them for a long fucking time and now consider getting back on them once in a while. still, for the first-line treatment, no way, especially since one can't be entirely sure that depression is what's the matter at that point.

paxil?
i got some horrible side effects from paxil. the withdrawal's even worse.
i have a friend who's on it that it works well for, but...
every medication works on everyone differently.

if you feel like you need the meds but don't like the side effects, maybe you should switch to another ssri.
good luck!

You got that right. I'm NEVER touching that shit again. I went through 2 weeks of torture coming off it.

Re: Paxil
 

Curious - did your doctor step down your dosage, or did you go cold turkey? If you stepped down, how gradually? I'm on Paxil CR, which is an extended release drug and supposedly doesn't have the same severity of side effects, but I'm still concerned about the effects of going off, which I will be doing in the next few months.

Sleepyjack, if you can use music to pull you out of the doldrum you ain't clinically depressed and your right you shouldn't be on anti depressants. When you are truly depressed music won't help, money won't help, sex won't help nothing helps. I always stayed away from any kind of drugs. I had to be hurting bad to take an aspirin. In the job I had before this one, half the staff was taking some kind of meds, but I took what they threw at me and continued to function with out any kind of medical help. Then I started a new job. The only think I wanted to do was sleep. I had to force myself to do even the simplest of tasks. I had a lot of physical symptoms to go with it. Suicide became one of the primary thoughts in my head. Finally I got so bad I had to do something so I allowed my wife to make an appointment for me. I am much better now. So even though anti-depressants are over used and abused they are a true life saver to some.

ok, i didn't realise the magnitude of some problems here. I never said i was clinically depressed, i just say whenever i am feeling down or whatever i use that stuff to help make everything better. I am sorry to have naivley said i try to stay away from chemicals, implying that evryone should, but again i didn't realise the magnitude. I let you know that i am empathetic with everyone tho and am sorry if i came across as a prick or something ;)

Re: Re: Paxil
 

I was on 40mg and went down in 10mg jumps over four weeks. Each subsequent week got worse. The final two, i felt like i was dying. But after that, everything got much easier and i returned to normal.

I was having electric shock sensations through my head at least every minute and my vision was delayed. I also had a constant shiver.

Good luck to you. Not everyone has bad withdrawal from paxil, i think i was just unlucky.

I'm currently on Welbutrin - have been for a couple months now. When my mother died this past January I had a very hard time coping. My husband urged me to make use of my company's mental health benefits and so I called them. After talking with a "counsellor" for a few minutes she gave me referrals for a local therapist.

In talking with my therapist I found that I've probably had clinical depression for years. I thought everyone had days when they didn't want to get out of bed, just getting up was too much work. And I mean having those types of days several times a week! I thought that was normal!

In my second visit my therapist suggested talking to my doctor about anti-depressants. My husband and I did some research, heard about the potential NASTY side effects and withdrawal symptoms from Paxil and decided on the Welbutrin.

I started at 150 mg 2x daily. The changes were gradual at first and my husband noticed them way before I did. The only way I can describe it is this. Picture a line going straight across the screen. Now picture that line with HUGE dips and peaks in it - going all the way to the top of the screen and the bottom. That was my life prior to Welbutrin. HUGE highs (ask my hubby about my cleaning fits :) ) and HUGE lows (although I never thought suicidal). After being on W for about a month I felt my life was almost a straight line again. Did it cure my misery about my mothers death? Nope - didn't expect it to. But it helped me cope; stopped the sudden crying jags (for no reason) and the anger. After another month on it my BD went through the roof (one of the potential side effects). So I tried going to 150 mg 1x day. I began to feel the dips again. So now I'm at 100 mg 2x. I still see my therapist (it's nice to have a non-biased person to talk to about anything) and my Doc & I are monitoring my BD to see how it goes. If I have to go back to 150 per day - I will. It wasn't really bad - still better than with nothing.

Two of my sisters are on anti-depressants. My mom used alcohol as her AD for awhile (but it had nothing to do with her death). I think there's some validity behind the thoughts that depression can be genetic.

Butthead - what "tests" are there to prove chemical imbalance? My therapist said the blood tests weren't reliable and the only other way as to do brain imaging (MRI or CAT scan).

I KNOW the drugs have helped me and I'll take them as long as they continue to help me. Once in awhile I'll go off them to see if I still need them. I had no problems going off them cold turkey (ran out before I could get in the see the Doc for a refill) so I know it's not a problem.

If you even THINK you might have a problem - PLEASE go see someone. I spent several years of my life in a fog because I didn't know any better. Life improved greatly when I met my husband and we married - but if it's a chemical imbalance then nothing short of getting it balanced will work.

I get so frustrated when people talk about "chemical levels" and "imbalances." It is all a hypothesis on why these pills make you happy. They cannot check how much seratonin you have...they would have to drill in to your brain to do so. No doctor i know would perform a biopsy to diagnose depression.

Take what works. Be patient, and be willing to try more than one medication. It is not a science in many ways...and becareful of anyone who is too sure of what they're saying. That said...NEVER take any SSRI on an irregular basis. That fucking you up is nearly the only guarantee in this whole mess.

I started paxil when i was under 18, which was since discovered to be very dangerous. I had had severe depression at that point in my life...and i know that they were just trying to help, but i do have some anger for the doc who gave it to me even those it wasn't FDA approved.

Perhaps as a side effect, i got drastically worse...i had panic attacks for the first time, and had no let up with my depression. Hospitalized for the first time, i was switched over to Celexa.

That didn't work either, and i began to cut myself pretty regularly. Switched to effexor, and had no improvement. Tapered off that, and went a year with out meds. I wasn't any better on or off, and so i figured off was cheaper.

Wellbutrin got a try after a nearly going back to cutting....but didn't really help much. A few months later, i quit that too. Nearly flunked college because of the depression and anxiety...but managed to turn it around with a little understanding from my profs.

These days i've got xanax for the panic attacks, but i can't use it much so i don't get addicted. Which is fine by me...i've had a spontaneous remission of the worst of my symptoms. I still get down sometimes, and i get panicky now and again. I don't know why...but for now, life is good.

The things i would reccomend to anybody facing these issues is to find someone who will listen when you need it-friends, family, etc... Becareful of overburdening them, but sometimes it just takes someone calming you down in the worst of it. That, and try to get regular exercise. Most of the drugs cause weight gain, and it's a big reason to quit them...i packed on 50 because i had to switch around so much...but not only will working out keep the pounds away, but helps take some edge off the blues.

MRI scans brain structure, PET scans 5HT neurotransmission, among other things. And let us not forget about spinal taps.

They check for metabolites in extracted fluids or use radioactive agents.

I'd probably start out with the more promising alternative methods.

Frowning Budah nipped it in the bud. i don't wanna spam boards by posting one or two sentences but i think he said it best by far. you don't want to anything other not exist. the colors of life and black and white, all sounds are noisy, every smile is fake, laughs are cynical and everyone's after you.... sometimes our brain is simply fucked up... i think it is far too easy for someone to say what will or will not help or cause or even is depression until tackled first hand... and then it can still be vastly different.

Hmm, that's great.

Your last post is a little hard to read.

...

Hopefully a mod will the delete the above message. Posted it on accident and due to me being six to eight feet from the monitor I couldn’t find the little edit button.

It’s odd to me how its’ simple to up the font but the buttons stay small.

Anyhow.

When you are severly depressed you do not want anything but to quit existing.

I realize that was a fair sized typo.. cut me a little slack, I had a toughtough day.

You really have to be careful. My advice is to take only as much as you really need to prevent yourself from becoming dangerous. I had a bad year last year, and a few people, both friends and medical proffessionals, were trying to medicate me to cheer me up. I'm still glad I didn't give in; my condition wasn't pleasant, but I wasn't a threat to myself or anyone else; I just wasn't that happy. Now that has passed, and I have no chemical dependancies to kick. Moreover, I <I>know</I> that it has passed, and I am not just happy because of meds.

That said, in a lot of cases, depression manifests itself as self-destructive tendancies, or even suicidal urges. The mood swings it causes can pose serious threats to relationships, especially when children are involved. If that is your situation, then I would urge you to get on drugs to control yourself; but not enough to really wipe you out. Some of the work in maintaining your sanity needs to come from you. It's the only way to make the results mean anything at all.

Thank you for your wisdom. :)

Sleepyjack, I understand where you are coming from. I never understood what depression really was until it happened to me. Even now I have trouble understanding why I just can't "shake it off". I didn't mean to come down on you. I was just trying to stress, that as bad as it is, the medication method is the only thing that is going to give many of us a chance to be normal again.

Something I found interesting while researching this for Balaniki:

SSRI's inhibit seratonin uptake to prevent depression right?

Welbutrin INCREASES seratonin (or the uptake. can't remember now) to prevent depression.

Too opposite approaches to the same goal. Shows they don't fully understand the cause, or there is more than one cause.

One solution does not fit all, so those of you talking in absolutes should reconsider. Drugs are working for my wife, and that's all that is important, because no one should have to live that way.

SSRIs block presynaptic neuronal uptake ("reuptake") just like Wellbutrin does, allowing for more synaptic serotonin so that hopefully more will bind to the postsynaptic neuron. Although Wellbutrin does a few other things and is less understood than SSRIs.

I firmly believe there is no one single cause of depression.

And WhoaitZ: I wasn't trying to be a dick, but that sentence and some others were missing words, making it difficult to follow. The "yeah, that's great" comment was something cute my partner said in response when I humorously read typos aloud. No offense intended and I apologize.

Wellbutrin inhibits the reuptake of norepinephrine and dopamine. I think that is how they think it works.

And also serotonin. You'll hear different claims on bupropions mechanism from many different credible sources leading me to believe that it's pointless to really make it a big point. However, I believe it affects DA and NE more than 5HT.

I've been on antidepressents for about four years now. I started out with Celexa. I guess I felt okay for a while. Then it didn't seem to do anything. Then I had Effexor--which I had a bad reaction to when I got off of it. Currently I take Prozac. There are some days I wonder if it even works. I have lupus so I'm familiar with having to find the "right" medicine to take. It's really a pain in the ass, I guess that's why I've stuck with the Prozac. My question is though, does your body ever just get immuned to this stuff and it's just not effective anymore???????

Ummm .. I think I'll stick with my drugs. I'm really not into people extracted fluid from my spine or pumping me full of radioactive agents.