I'd have to say that The Journal Comic (
http://www.drewweing.com/index.html) Is one of the my absolute favorites. It potrayes the life of the Geek in such true light. Highly HIGHLY Reccomended.
I'm also a big fan of Wigu (
http://www.wigu.com/ ) For the brillant Silliness it conveys. Three out of Every Four Wigu Strips make me laugh out loud.