If nothing is installed "between" them, it should be okay, but there's no guarantee. XP drive enumeration can cause weird results on some hardware. Try it with safe-boot to make sure so you can re-order drive letters if needed. Better than allowing the usual horde of software to start and freak fantastic because letters changed.
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There are a vast number of people who are uninformed and heavily propagandized, but fundamentally decent. The propaganda that inundates them is effective when unchallenged, but much of it goes only skin deep. If they can be brought to raise questions and apply their decent instincts and basic intelligence, many people quickly escape the confines of the doctrinal system and are willing to do something to help others who are really suffering and oppressed." -Manufacturing Consent: Noam Chomsky and the Media, p. 195
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