Blonddie: Avoid caffeine and maybe take some over-the-counter medication that makes you a bit drowsy? For some bizarre reason Sudafed Cold & Flu will put me into one of those apathetic "I just don't care" states of mind. As long as you aren't a frequent flyer, I don't see how this would cause any problems.
I have a natural interest in flight, though I'll never do anything career-wise with it, or spend any sort of major money learning to fly or anything.
I'm actually flying out to Colorado here in a few weeks and am looking forward to it. I know the area around the airport real well and live relatively close to it, so immediately after take-off, I like to try to identify roads and buildings since they look completely different from the air. Likewise, during landings, I like to watch the ground as it gets closer, look at the roads, buildings, etc. Nighttime is especially interesting in bigger cities, looking at the lights and what-not. Even when 30,000 feet above.
By the time the novelty of take-off and things becoming too small to really care about it's just about time for airline peanuts and beverages. A lot of the airlines even have in-flight music that you can listen to on a headset to get your mind off of things.
The other thing you could do is if you enjoy reading, get to the airport a bit early with a book you can really get into and start getting into it before boarding so you're anxious to continue reading once you're situated in your seat.
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