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The main effect of exceeding your MHR is that your muscles start to respirate aneaobically, which builds up. Also, its not really good for burning fat. Muscle wasting is the end product, as you rightly mention.
The fact that her heart rate reaches 178 is not the main problem, IMO.
MHR is a method that one should use to tailor your workplan. Its a zone that you should strive to exercise in. From what you say, it sounds like she's doing her set routine, and her HR is thus going above the MHR.
The cardiologist might not find anything wrong with her, in which case she should go consult a trainer who will give her a routine that will best complement her. As you mention, the excercise has yielded benefits over the last two years, with no negatives as yet. i think that a slightly less strenous cardio workout will still give her all the same benefits, plus a few more.
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