Your best bet is to fly into Germany rather than London. London is too pricey and most of the bars close at 10pm due to some ridiculous law held over from WWII.
If you fly into Frankfurt, there is a train station there that can take you anywhere you want. I love Amsterdam and Brussells, and those two are only about a half day away from central Germany. I would skip France unless you like to be insulted and feel like a complete moron because you can't speak Frog.
Prague is beautiful and is one of the few cities in Europe that wasn't devasted by the Nazi's. Poland can be boring, but if you go that far east, you might as well go to Russia.
Paris gets old real quick. Brussells is the poor-man's Paris but has a good night life and people that will speak English to you. Amsterdam is on the top of my list; pot, Van Gogh, and hot dutch girls. London sucks. Dublin is cool but that will eat up your budget getting there; although, I've heard there is a ferry that goes from Northern France to there. Germany is very cool and the people are really friendly but don't tend to understand sarcasm. I've never been to Italy but I've also heard good things; just don't bring your special lady friend unless, of course, you want to lose her to Luigi.
Hostels, a train pass, and a couple credit cards are a must. A good backpack that will support your back is a good idea. Hotels, car rentals, and the Red Light Districts will devour your money. Carry minimal cash and make sure to make a photocopy of your passport before leaving; you'll be in a world of hurt if you lose you passport.
Hope this helps.
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