I like the polys as well, but the cost deters me. With as much doin' it as I do it would cost me around 3-4 times as much a week... ouch.
Pros: They do transfer heat better, I noticed after running out one night after switching to latex, they are nice and sheer, and they don't smell to high heaven.
Cons: They don't stretch (though I've never had one fail), and they crinkle. Yes, they crinkle. It can be kind of distracting.
Oh, and as for disease protection, polyurathane is a non-porous material, its just doesn't have FDA approval yet.
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