I came across this piece in the NYTimes a few months ago, and really liked the idea of a tiny home:
http://www.nytimes.com/2010/04/22/garden/22garage.html
I nannied for a family that lived in a small 2-bedroom house with an upstairs finished attic, 1 bathroom, and a laundry room/pantry. It was just about perfect at that size--and easy to keep clean. I miss that house. My current place is too big for 2 people--we have extra rooms that seem to do nothing but collect junk that we can then shut a door on.
I think it's time for a massive cleaning spree.