In no particular order, here are a few that I read...
Pharyngula - Evolutionary biologist and outspoken atheist, PZ Myers, discusses atheism, science, politics, and more.
Why Evolution is True - Jerry Coyne, another atheist evolutionary biologist, writes about... atheism, science, and politics. This blog is more science-heavy than Pharyngula.
Food Politics - Exactly what it sounds like. A blog about the politics of food.
Hardcore Zen - Zen priest, author, and punk rocker Brad Warner writes about Zen Buddhism and other stuff.
Becoming Jennie - Former porn star, Jennie Ketcham (Penny Flame) chronicles her journey as she learns to make real emotional connections with the human beings around her. Unlike other former porn stars who leave the business to deal with personal issues, Jennie does not blame porn on her troubles in any way.
High on Sex - Sex stuff.
Eros Blog - More sex stuff.
Whatever - Author John Scalzi writes about... well, lots of things. Sci-fi/geek stuff mostly.