Different chicks, different methods. Also depends what you're looking for (long term girlfriend vs. meeting as many women as possible). I met one of my favorite current girls on a popular strip downtown on my motorcycle, also known as poser lane...
She was checking out my ducati, said she's never been on one. I took her for a ride, brought her back to her friends 1 hour later and that's when she told her friends she was going to spend the rest of the evening with me.
Pickup lines suck. Be witty, be funny, entertain her and her friends and just be somebody who she could see herself with. Also, invest in some nice shoes... for some reason, girls look at a guy's shoes.