Pharyngula is opinion-oriented, yes, but it does not bastardize science at all. One need not appease religion to be a good scientist. In fact, I'd argue that appeasing religion is why we're where we are right now in regards to creationism and evolution. Some religion deserves bashing, and creationism - which, btw, is what Pharyngula targets most - is definitely one of those aspects.
Honestly, if you want to know what kind of crazy stuff is out there regarding the spread of creationism, Pharyngula is a
great blog to read. Case in point:
Ten Questions to Ask Your Biology Teacher About Intelligent Design