I usually clean my mouse pad (cloth with foam underneath) by soaking in soapy water and then scrubbing it a bit. After that I drain the water and rinse it out (along with ringing out the soapy water). After that I leave it hanging in the sun for most of a day to dry.
P.S. I agree that getting an optical mouse would avoid this porblem, but I just haven't gotten around to getting one myself
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