4-8 reps, generally about 2 sets.
When you do such low reps, you want to be at the very edge of your weight lifting ability. Say you can bench 200 lbs just one time (your max bench), then you would do 2 sets of 180lbs. Believe me, it'll freakin hurt (as its supposed to!).
Also, sometimes a warmup set helps where you just push 60% max weight 4-8 times. You won't fatigue, it's just to get the blood flowing.
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