I'll start with.....
Friendly Hostility
by K. Sandra Fuhr
http://www.friendlyhostility.com
A comic based on the adventures of two male roommates, which has supernatural overtones and lots of gay jokes. The twist? These two are a gay couple. This is a spin-off of Fuhr's popular "Boy Meets Boy" comic which focuses on the lives of Fox Maharassa and Collin Sri'vastra. It brings in a lot of backstory and often focuses on Fox's family. Some of the best parts include Uncle Rafi, a sex fiend and priest for the Church of Satan. Despite being a spin-off, this comic is stand-alone great. I got into it before I even read Boy Meets Boy, and didn't even realize that it was the same author and artist.