I can offer a couple tips
I started running earlier this summer, I'd never really been a runner before (bicycle was my excercise of choice).
now, I still like to bike, but i really dig running.
1. start small. of course. it helps if you're at least generally in shape from lots of walking.
1a. but - remember, the 1st 10 mins are the worst. at some point, you need to figure out that you need to push yourself through the beginning of it.
2. shoes shoes shoes. go to a shop, have them help you figure out if you pronate or supinate. then choose good shoes accordingly.
3. bra - I love my Champion for running. it's not one of the cheap Target ones, it's one of the pricier Champions. go to a place that sells em and try em on whilst jumping up and down.
4. Hydration is very important. before and after. and make sure to eat some
healthy carb after running, it *really* helps with recovery (meaning, less soreness the next day).
um, that's all off the top of my head.
best of luck to you, it's a great feeling once you get it goin