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Use a bit of common sense. High rep training will build endurance, and it is better for weight loss. Normally a person would consider weight training and cardio separate things, but when it comes to high rep they are the same. Think about it: both use a relatively light weight (compared to what the muscles can handle) and both involve a lot of repetitions. It doesn't matter where the weight comes from, whether from the body or from a barbell.
20+ reps will build muscle endurance, but you might have to do many more reps than that to strengthen the heart. Anything less than 20 isn't effective for muscle endurance or fitness.
So I'd recommend doing whatever is most fun/convenient/easier to stick with. Experiment with both, rotate, whatever. If it gets your heart going fast, for a decent period of time, you'll get fitter. It's not really that complicated.
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