As an Me to an Mo, I want to say this: Don't find Smite Hex. And DEFINITELY don't tell anybody where it is, if you do.
I currently use 6 hexes, 1 spell (shatter enchantment) and a res sig.
I used to just do domination magic, but decided.. it's really easy in this game to spread out, instead of focusing on one thing.. you spend way, way too many skill points, and runes, even just major runes, can help get your skills where you want them.. I'm around ~10-13 in fast casting, dom, and illusion magic, and i only have 1 rune on (don't want to spoil all my pricey armor just yet..) The illusion magic is great against warriors!! People learn to take out the Me pronto, to save their monk, so I cast a few hexes on the warrior thats charging at me, slow him down, and back up while somebody nukes the hell out of him, once he's out, then it's on to backfire and all that goodness like usual.