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Mono and depression have some sort of correlation. My mom had mono which lead to a pretty major depression. There's also a correlation between going to college and depression. 2 things factor in here, 1) we generally go to college about the age when mental illness tends to appear and 2) college is a HUGE change. This could be a one time event you can work through or as you said gentics could be playing a role and this may be a lifetime struggle. Sometimes antidepressents can help you get over that hump and then as your life straightens out you can ween off of them. Most colleges offer free counseling. It sounds like it wouldn't hurt to give it a try.
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