The problem with the DE is that it's not a very reliable weapon at ALL. They're famous for their malf-a-minute fickleness; you do NOT want to be doing a tap-rack-bang drill as an 1800-lb Kodiak is barreling down on you. This is why guides ( if they carry a hangun at all; most prefer rifles ) carry a revolver.
Secondly, almost any firearm can shoot through a wall and be capable of killing people on the other side. Even a .22-calibre pistol can accomplish this if it's just shooting through sheetrock, masonite, or plyboard. Now, if it's masonry we're talking about ( brick or stone ) then almost no handgun can do that. The new .500 S&W might be able to penetrate a fair bit, and almost any bullet will -crack- masonry, but penetrate with enough force to kill? Doubtful.
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